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Background
In 2021, the World Health Organization (WHO) has provided the latest update on processing and evaluating semen analysis.
Objectives
To assess (i) the rate of discordance in semen parameters categorization across three different WHO reference values (namely WHO21, 2010 and 1999) and (ii) the clinical differences among discordant semen analyses from a cohort of primary infertile men.
...
Background
Reinke crystals are structures pathognomonic for Leydig cells, which have the important function of testosterone production and are vital for male reproductive health. These crystalline inclusions are thought to be of protein origin; however, the molecular composition has not yet been resolved.
Objectives
This review summarizes all available information regarding Reinke crystal's characteristics...
Objectives
To challenge a vapour fast freezing (VFF) cryopreservation procedure (conventional VFF) with several vitrification protocols and VFF conducted with small semen volumes (10 μl, microVFF), in order to implement a procedure for sperm banking in subjects with small sperm number.
Materials and methods
Conventional VFF was conducted with test yolk buffer (TYB) as freezing medium and 500 μl...
Background
The mechanism by which low androgen status inhibit erectile function has not yet been clearly elucidated. Neurogranin (Ng) is a Ca2+‐sensitive calmodulin binding protein that is expressed in endothelial cells and regulates eNOS function.
Objectives
To investigate whether low androgen status inhibit erectile function by regulating the Ng/CaN/AKT/eNOS pathway in the penile cavernous tissue...
Background
Transrectal ultrasound (TRUS) parameters are not standardized, especially in men of reproductive age. Hence, the European Academy of Andrology (EAA) promoted a multicenter study to assess the TRUS characteristics of healthy‐fertile men (HFM) to establish normative parameters.
Objectives
To report and discuss the prostate and seminal vesicles (SV) reference ranges and characteristics...
Background
Addiction is a global problem that has many negative consequences on human health as well as the quality of life.
Objectives
This review aimed to assess the effect of addiction on human male fertility.
Methods
A systematic review was conducted on various electronic sites.
Results
The initial literature search identified a total of 5239 articles in all searched databases. After removing...
Background
Angiotensin‐converting enzyme 2 and transmembrane protease serine 2 are critical factors of virus transmission. Expression of angiotensin‐converting enzyme 2 is highest in testes, and testicular function and testosterone levels were affected by coronavirus disease 2019. Low testosterone levels are related to infections, especially respiratory tract infections, and could worsen clinical...
Background
The COVID‐19 pandemic has led the international community to conduct extensive research into potential negative effects of the disease on multiple organs and systems in the human body. One of the most discussed areas is potential of the virus to compromise the testicular function. However, the lack of prospective studies on this topic makes it impossible to draw reliable conclusions on...
Background
The effects of an mRNA COVID‐19 vaccine on spermatozoa parameters are not known. The aim of this study was to evaluate the effect of the BNT162b2 mRNA COVID‐19 vaccine on human semen, comparing spermatozoa parameters before and after vaccine inoculation.
Materials and methods
In this single‐center prospective study, voluntary subjects who received mRNA vaccines from February to July...
Background
Smoke‐free tobacco via moist oral snuff (snus) is used daily in more than 20% of Swedish men. Negative effects of cigarette smoking on sperm parameters are well documented, unlike for snuff, despite relevance also for other smoke‐free nicotine products.
Objectives
We wanted to investigate whether reproductive parameters differed between users and non‐users of snuff, and whether the amount...
Background
There is evidence that, after severe acute respiratory syndrome coronavirus 2 infection, male reproductive function and semen quality may be damaged
Objectives
To evaluate a panel of inflammatory mediators in semen in patients recovered from coronavirus disease 2019.
Material and methods
Sexually active men with previous severe acute respiratory syndrome coronavirus 2 infection and...
Importance
Low testosterone levels in males have been linked with increase in proinflammatory cytokines—a primary culprit in COVID‐19 disease progression—and with adverse COVID‐19 outcomes. To date, however, no published studies have assessed the effect of testosterone therapy on COVID‐19 outcomes in older men.
Objective
To examine whether testosterone therapy reduced disease progression in older...
Background
The primary function of testicular Leydig cells (LCs) is to produce testosterone (T). In vitro culture of the cells represents a very important approach to study androgen production and its regulations. Various methods have been developed for the enrichment of the cells from the testes. However, getting cells in large numbers with high purity and viability is still challenging. Here, we...
Background
The development of covid‐19 vaccinations represents a notable scientific achievement. Nevertheless, concerns have been raised regarding their possible detrimental impact on male fertility
Objective
To investigate the effect of covid‐19 BNT162b2 (Pfizer) vaccine on semen parameters among semen donors (SD).
Methods
Thirty‐seven SD from three sperm banks that provided 216 samples were...
Introduction
Semen analysis (SA) plays a key role in guiding treatments of male reproductive diseases and infertility due to male factors; however, it remains challenging to conduct an accurate SA due to lack of standardization, highly subjective assessments, and problems with automated procedures. Therefore, quality assurance (QA) and teaching courses are essential for making the laboratory results...
Background
C‐reactive protein (CRP), as a marker of inflammation, may be closely related to erectile dysfunction (ED), however, there is no meta‐analysis exists for it.
Objectives
We aimed to verify the relationship between CRP and erectile dysfunction and to explore the changes of CRP levels in ED patients after first‐line treatment.
Materials and methods
We searched databases including the...
Background
Erectile function is usually impaired after radiation therapy in prostate cancer patients. eNOS is a key enzyme in the process of erection. Mitochondria‐associated membranes (MAMs) are closely contacted with the production and bioactivity of eNOS.
Objective
To study the mechanism of icariin improves the erectile function of rats treated with prostate radiation by controling the expression...
Background
Surveys of gender diversity in editorial boards of journals have been conducted in several disciplines, but not in andrology.
Objectives
The present study was designed to investigate the gender distribution of editorial boards of andrology journals.
Methods
A total of eight andrology journals were included in the study, and the gender information and geographical location of editors...
Background
Male factor contributes to up to 50% of cases of couples experiencing infertility. Cannabis is one of the most commonly used recreational drugs, and its effects on the reproductive system have been largely debated in the literature.
Objectives
The aim of this study is to evaluate the effect of recreational cannabis use on total T (tT) levels, gonadal status, and sperm parameters in a...
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